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Carla Ghelardini Selected Research

Sulfonamides

11/2019Spirocyclic sulfonamides with carbonic anhydrase inhibitory and anti-neuropathic pain activity.
9/2019Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.
12/2017Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases.
12/2016Carbonic anhydrase inhibition for the management of cerebral ischemia: in vivo evaluation of sulfonamide and coumarin inhibitors.
5/20156-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.
4/2015A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects.

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Carla Ghelardini Research Topics

Disease

105Pain (Aches)
04/2024 - 10/2004
79Neuralgia (Stump Neuralgia)
04/2024 - 12/2002
41Hypersensitivity (Allergy)
06/2023 - 08/2006
37Hyperalgesia
11/2023 - 09/2002
33Neoplasms (Cancer)
10/2023 - 01/2013
18Inflammation (Inflammations)
12/2023 - 11/2007
14Colitis
10/2023 - 01/2019
14Rheumatoid Arthritis
06/2023 - 01/2013
13Osteoarthritis
06/2023 - 01/2013
10Chronic Pain
10/2023 - 07/2013
9Visceral Pain
10/2023 - 12/2019
8Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 03/2012
8Amnesia (Dissociative Amnesia)
04/2015 - 03/2002
7Arthritis (Polyarthritis)
10/2022 - 01/2016
7Painful Neuropathy
09/2018 - 06/2014
6Colonic Neoplasms (Colon Cancer)
02/2018 - 01/2014
6Peripheral Nervous System Diseases (PNS Diseases)
03/2017 - 01/2009
5Gliosis
10/2023 - 01/2013
4Edema (Dropsy)
12/2023 - 08/2008
4Cognitive Dysfunction
12/2022 - 03/2002
4Body Weight (Weight, Body)
08/2022 - 06/2010
4Neuroinflammatory Diseases
07/2022 - 01/2017
4Epilepsy (Aura)
04/2022 - 05/2018
4Abdominal Pain (Pain, Abdominal)
12/2020 - 12/2016
4Neuroblastoma
11/2019 - 10/2013
4Migraine Disorders (Migraine)
04/2013 - 09/2002
3Ischemia
12/2023 - 04/2016
3Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2023 - 01/2017
3Nervous System Diseases (Neurological Disorders)
12/2022 - 12/2017

Drug/Important Bio-Agent (IBA)

56Oxaliplatin (Eloxatin)FDA LinkGeneric
05/2023 - 05/2010
24Carbonic Anhydrases (Carbonic Anhydrase)IBA
10/2022 - 04/2015
22Morphine (MS Contin)FDA LinkGeneric
01/2024 - 09/2002
18Protein Isoforms (Isoforms)IBA
12/2021 - 04/2015
17Opioid Analgesics (Opioids)IBA
01/2024 - 09/2004
13Analgesics (Analgesic Drugs)IBA
04/2024 - 09/2002
132,4-dinitrofluorobenzene sulfonic acidIBA
10/2023 - 12/2019
12Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
12/2022 - 01/2009
10Proteins (Proteins, Gene)FDA Link
04/2022 - 10/2009
9LigandsIBA
01/2022 - 12/2011
9AntioxidantsIBA
06/2021 - 11/2011
8CarrageenanIBA
12/2023 - 08/2008
8Carbonic Anhydrase InhibitorsIBA
01/2023 - 04/2015
7Paclitaxel (Taxol)FDA LinkGeneric
11/2023 - 11/2015
7Streptozocin (Streptozotocin)FDA Link
10/2023 - 03/2008
7Acetylcarnitine (Alcar)IBA
10/2023 - 12/2002
7SodiumIBA
12/2022 - 04/2011
6Freund's AdjuvantIBA
01/2023 - 01/2013
6N-Methylaspartate (NMDA)IBA
12/2022 - 12/2002
6Antineoplastic Agents (Antineoplastics)IBA
12/2021 - 07/2013
6PlatinumIBA
12/2021 - 11/2014
6SulfonamidesIBA
11/2019 - 04/2015
5Pregabalin (Lyrica)FDA Link
10/2023 - 04/2011
5Sulfonic AcidsIBA
10/2023 - 01/2020
5dimiracetamIBA
12/2022 - 03/2008
5Glutamic Acid (Glutamate)FDA Link
12/2022 - 11/2014
52,4-dinitrobenzenesulfonic acidIBA
07/2022 - 01/2020
5Purinergic P1 Receptors (Adenosine Receptor)IBA
10/2021 - 01/2019
5EnzymesIBA
01/2021 - 10/2009
5BenzenesulfonamidesIBA
01/2021 - 06/2018
5isothiocyanic acidIBA
03/2019 - 11/2016
5Protein Kinase CIBA
04/2013 - 08/2004
42,4-dinitrobenzeneIBA
10/2023 - 01/2020
4LipopolysaccharidesIBA
12/2022 - 08/2019
4Potassium Channels (Potassium Channel)IBA
02/2022 - 11/2016
4GlucosinolatesIBA
02/2022 - 11/2018
4AcidsIBA
01/2022 - 10/2009
4N(6)- (3- iodobenzyl)- 5'- N- methylcarboxamidoadenosineIBA
01/2022 - 01/2020
4Carbonic Anhydrase IXIBA
12/2021 - 11/2017
4Neuroprotective AgentsIBA
01/2021 - 01/2009
4Thioctic Acid (Lipoic Acid)IBA
01/2021 - 01/2013
4Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
12/2020 - 01/2017
4Opioid Receptors (Opioid Receptor)IBA
01/2020 - 11/2014
4Caffeine (No Doz)FDA LinkGeneric
01/2019 - 09/2002
4Gabapentin (Neurontin)FDA LinkGeneric
04/2018 - 07/2015
4Indomethacin (Indometacin)FDA LinkGeneric
01/2017 - 09/2002
4Scopolamine (Hyoscine)FDA Link
04/2015 - 03/2002
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2024 - 01/2018
3Monoclonal AntibodiesIBA
04/2024 - 01/2018
3palmidrolIBA
04/2024 - 02/2022
3Anticonvulsants (Antiepileptic Drugs)IBA
01/2024 - 01/2019
3Antidepressive Agents (Antidepressants)IBA
01/2024 - 11/2011
3Hydrogen Sulfide (Sulfide, Hydrogen)IBA
12/2023 - 07/2017
3erucinIBA
12/2023 - 03/2019
3CalciumIBA
12/2023 - 09/2008
3DDD-028IBA
11/2023 - 01/2021
3Duloxetine Hydrochloride (Cymbalta)FDA Link
10/2023 - 09/2015
3Formyl Peptide Receptors (Formyl Peptide Receptor)IBA
06/2023 - 01/2020
3Liposomes (Liposome)IBA
05/2023 - 11/2015
3EndocannabinoidsIBA
05/2023 - 12/2020
3CoumarinsIBA
01/2023 - 01/2017
3Conotoxins (Conotoxin)IBA
12/2022 - 10/2014

Therapy/Procedure

30Therapeutics
02/2022 - 11/2011
23Drug Therapy (Chemotherapy)
04/2024 - 07/2013
8Intra-Articular Injections
06/2023 - 04/2011
8Analgesia
01/2020 - 06/2003
6Aftercare (After-Treatment)
01/2023 - 05/2014
6Oral Administration
12/2022 - 04/2011
5Ligation
01/2021 - 01/2009
3Laser Therapy (Surgery, Laser)
05/2023 - 11/2017
3Injections
01/2023 - 01/2018